| UniProt functional annotation for P42404 | |||
| UniProt code: P42404. |
| Organism: | Bacillus subtilis (strain 168). | |
| Taxonomy: | Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus. | |
| Function: | Catalyzes the isomerization between 3-hexulose 6-phosphate and fructose 6-phosphate. Together with HxlA, may act as a formaldehyde detoxification system. | |
| Catalytic activity: | Reaction=D-arabino-hex-3-ulose 6-phosphate = beta-D-fructose 6- phosphate; Xref=Rhea:RHEA:25900, ChEBI:CHEBI:57634, ChEBI:CHEBI:58542; EC=5.3.1.27; | |
| Pathway: | One-carbon metabolism; formaldehyde assimilation via RuMP pathway; D-fructose 6-phosphate from D-ribulose 5-phosphate and formaldehyde: step 2/2. | |
| Subunit: | Homotetramer. {ECO:0000269|PubMed:15363790}. | |
| Induction: | By formaldehyde, under the control of HxlR. Not induced by methanol, formate, or methylamine. | |
| Similarity: | Belongs to the SIS family. PHI subfamily. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.