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UniProt functional annotation for P44490 | ||
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| UniProt code: P44490. |
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| Organism: | |
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Haemophilus. |
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| Function: | |
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. {ECO:0000255|HAMAP-Rule:MF_00057}. |
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| Catalytic activity: | |
Reaction=3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy- beta-D-manno-octulosonate + diphosphate; Xref=Rhea:RHEA:23448, ChEBI:CHEBI:33019, ChEBI:CHEBI:37563, ChEBI:CHEBI:85986, ChEBI:CHEBI:85987; EC=2.7.7.38; Evidence={ECO:0000255|HAMAP- Rule:MF_00057}; |
| Pathway: | |
Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno- octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3- deoxy-D-manno-octulosonate and CTP: step 1/1. {ECO:0000255|HAMAP- Rule:MF_00057}. |
| Pathway: | |
Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. {ECO:0000255|HAMAP-Rule:MF_00057}. |
| Subcellular location: | |
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00057}. |
| Similarity: | |
Belongs to the KdsB family. {ECO:0000255|HAMAP- Rule:MF_00057}. |
Annotations taken from UniProtKB at the EBI.