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UniProt functional annotation for Q8BWR8 | ||
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| UniProt code: Q8BWR8. |
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| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
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| Function: | |
Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity (By similarity). {ECO:0000250}. |
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| Subunit: | |
Interacts with GTP-bound RhoA and RhoB. Interacts with both GTP- and GDP-bound RhoA. Interacts with KRT18 (By similarity). {ECO:0000250}. |
| Subcellular location: | |
Cytoplasm, perinuclear region {ECO:0000250}. |
| Similarity: | |
Belongs to the RHPN family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.