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UniProt functional annotation for P83256 | ||
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| UniProt code: P83256. |
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| Organism: | |
Pireneitega luctuosa (Tangled nest spider) (Paracoelotes luctuosus). |
| Taxonomy: | |
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Araneae; Araneomorphae; Entelegynae; Amaurobiidae; Pireneitega. |
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| Function: | |
Binds at site 4 of sodium channels (Nav) and inhibits the fast inactivation of cockroach channels. This toxin is active only on insects. Has a potent activity against S.litura larvae. {ECO:0000269|PubMed:10971590}. |
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| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Expressed by the venom gland. {ECO:0000269|PubMed:10971590}. |
| Domain: | |
The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. |
| Mass spectrometry: | |
Mass=4037.9; Method=MALDI; Evidence={ECO:0000269|PubMed:10971590}; |
| Similarity: | |
Belongs to the neurotoxin 07 (Beta/delta-agtx) family. 02 (aga-3) subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.