UniProt functional annotation for Q8ZUJ3

UniProt code: Q8ZUJ3.

Organism: Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827).
Taxonomy: Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae; Pyrobaculum.
 
Function: Toxic component of a type II toxin-antitoxin (TA) system (By similarity). Has ribonuclease activity. Has a slow ssDNA exonuclease activity. {ECO:0000250, ECO:0000269|PubMed:22539524}.
 
Cofactor: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00265, ECO:0000269|PubMed:14734548, ECO:0000269|PubMed:22539524};
Activity regulation: Inhibited by EDTA. {ECO:0000269|PubMed:22539524}.
Subunit: Homodimer, 2 of which then form a homotetramer. {ECO:0000269|PubMed:14734548}.
Similarity: Belongs to the PINc/VapC protein family. {ECO:0000255|HAMAP-Rule:MF_00265}.

Annotations taken from UniProtKB at the EBI.