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UniProt functional annotation for Q9P2J2 | ||
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| UniProt code: Q9P2J2. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Functions in dendrite outgrowth and synapse maturation. {ECO:0000250}. |
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| Subunit: | |
Interacts with MAGI2 and SHANK1. {ECO:0000250}. |
| Subcellular location: | |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Enriched at the excitatory synapses in mature neurons. {ECO:0000250}. |
| Developmental stage: | |
Expressed in a wide variety of tissues at 8 and 14 weeks of gestation. {ECO:0000269|PubMed:11991715}. |
| Domain: | |
The PDZ-binding motif mediates interactions with MAGI2 and SHANK1. {ECO:0000250}. |
| Similarity: | |
Belongs to the immunoglobulin superfamily. Turtle family. {ECO:0000305}. |
| Sequence caution: | |
Sequence=BAA92593.1; Type=Erroneous initiation; Evidence={ECO:0000305}; |
Annotations taken from UniProtKB at the EBI.