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UniProt functional annotation for P0A6W9 | ||
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| UniProt code: P0A6W9. |
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| Organism: | |
Escherichia coli (strain K12). |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. |
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| Catalytic activity: | |
Reaction=ATP + L-cysteine + L-glutamate = ADP + H(+) + L-gamma- glutamyl-L-cysteine + phosphate; Xref=Rhea:RHEA:13285, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:35235, ChEBI:CHEBI:43474, ChEBI:CHEBI:58173, ChEBI:CHEBI:456216; EC=6.3.2.2; |
| Pathway: | |
Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2. |
| Similarity: | |
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.