PDBsum entry 1um4

Immune system

PDB id: 1um4

Contents

Protein chains

219 a.a. *

217 a.a. *

Ligands

SH4

Waters ×242

* Residue conservation analysis

PDB id:

1um4

Name:

Immune system

Title:

Catalytic antibody 21h3 with hapten

Structure:

Antibody 21h3 l chain. Chain: l. Engineered: yes. Antibody 21h3 h chain. Chain: h. Engineered: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562

Biol. unit:

Dimer (from PQS)

Resolution:

1.80Å R-factor: 0.223 R-free: 0.249

Authors:

A.E.Beuscher Iv,J.Reuter,A.J.Olson,F.E.Romesberg,P.G.Schultz, P.Wirsching,K.D.Janda,R.A.Lerner,R.C.Stevens

Key ref:

A.E.Beuscher IV et al. Structural studies of an efficient catalytic antibody operating by ping-Pong and induced fit mechanisms. To be published, .

Date:

23-Sep-03 Release date: 05-Oct-04

Protein chain

No UniProt id for this chain

Struc: 219 a.a.

Protein chain

Q6PYX1  (Q6PYX1_HUMAN) -  Hepatitis B virus receptor binding protein (Fragment) from Homo sapiens

Seq: 348 a.a.

Struc: 217 a.a.*

* PDB and UniProt seqs differ at 10 residue positions (black crosses)