PDBsum entry 1u8k

Immune system

PDB id: 1u8k

Contents

Protein chains

214 a.a. *

228 a.a. *

Ligands

LEU-GLU-LEU-ASP-LYS-TRP-ALA-SER-LEU

Waters ×135

* Residue conservation analysis

PDB id:

1u8k

Name:

Immune system

Title:

Crystal structure of the HIV-1 cross neutralizing monoclonal antibody 2f5 in complex with gp41 peptide leldkwasl

Structure:

Antibody 2f5 (light chain). Chain: a. Antibody 2f5 (heavy chain). Chain: b. Gp41 peptide. Chain: c. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Synthetic: yes. Human immunodeficiency virus 1. Organism_taxid: 11676. Other_details: synthetic peptide

Biol. unit:

Trimer (from PQS)

Resolution:

2.24Å R-factor: 0.215 R-free: 0.246

Authors:

S.Bryson,J.-P.Julien,E.F.Pai

Key ref:

S.Bryson et al. Crystal structure of the HIV-1 cross neutralizing monoclonal antibody 2f5 in complex with gp41 peptides and peptide mimetics. To be published, .

Date:

06-Aug-04 Release date: 05-Oct-04

Protein chain

No UniProt id for this chain

Struc: 214 a.a.

Protein chain

No UniProt id for this chain

Struc: 228 a.a.