PDBsum entry 1u5f

Signaling protein

PDB id: 1u5f

Contents

Protein chain

119 a.a. *

Ligands

SO4 ×2

Waters ×8

* Residue conservation analysis

PDB id:

1u5f

Name:

Signaling protein

Title:

Crystal structure of the ph domain of skap-hom with 8 vector-derived n-terminal residues

Structure:

Src-associated adaptor protein. Chain: a. Fragment: ph domain, residues 109-248. Synonym: skap55 homologue. Engineered: yes. Mutation: yes

Source:

Mus musculus. House mouse. Organism_taxid: 10090. Gene: scap2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Dimer (from PQS)

Resolution:

1.90Å R-factor: 0.227 R-free: 0.246

Authors:

Y.Tang,K.D.Swanson,B.G.Neel,M.J.Eck

Key ref:

Y.Tang et al. Structural basis for the dimerization and phosphoinositide specificity of the src kinase-Associated phosphoproteins skap55 and skap-Hom. To be published, .

Date:

27-Jul-04 Release date: 26-Jul-05

Protein chain

Q3UND0  (SKAP2_MOUSE) -  Src kinase-associated phosphoprotein 2 from Mus musculus

Seq: 358 a.a.

Struc: 119 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.?