PDBsum entry 1u5d

Signaling protein

PDB id: 1u5d

Contents

Protein chains

108 a.a. *

Ligands

SO4 ×7

Waters ×427

* Residue conservation analysis

PDB id:

1u5d

Name:

Signaling protein

Title:

Crystal structure of the ph domain of skap55

Structure:

Src kinase-associated phosphoprotein of 55 kda. Chain: a, b, c, d. Fragment: ph domain (residues 106-213). Synonym: skap55. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: hsskap55. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Dimer (from PQS)

Resolution:

1.70Å R-factor: 0.168 R-free: 0.185

Authors:

Y.Tang,K.D.Swanson,B.G.Neel,M.J.Eck

Key ref:

Y.Tang et al. Structural basis for the dimerization and phosphoinositide specificity of the src kinase-Associated phosphoproteins skap55 and skap-Hom. To be published, .

Date:

27-Jul-04 Release date: 26-Jul-05

Protein chains

Q86WV1  (SKAP1_HUMAN) -  Src kinase-associated phosphoprotein 1 from Homo sapiens

Seq: 359 a.a.

Struc: 108 a.a.*

* PDB and UniProt seqs differ at 4 residue positions (black crosses)