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PDBsum entry 1tyn

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protein ligands links
Hydrolase(serine protease) PDB id
1tyn
Jmol PyMol
Contents
Protein chain
223 a.a. *
Ligands
CTA
Waters ×121
* Residue conservation analysis
PDB id:
1tyn
Name: Hydrolase(serine protease)
Title: Atomic structure of the trypsin-cyclotheonamide a complex: lessons for the design of serine protease inhibitors
Structure: Beta-trypsin. Chain: a. Engineered: yes
Source: Bos taurus. Cattle. Organism_taxid: 9913
Resolution:
2.00Å     R-factor:   0.169     R-free:   0.222
Authors: A.Y.Lee,M.Hagihara,R.Karmacharya,M.W.Albers,S.L.Schreiber, J.Clardy
Key ref: A.Y.Lee et al. (1993). Atomic structure of the trypsin-Cyclotheonamide a complex: lessons for the design of serine protease inhibitors. J.Am.Chem.Soc., 115, 12619.
Date:
19-Sep-94     Release date:   26-Jan-95    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P00760  (TRY1_BOVIN) -  Cationic trypsin
Seq:
Struc:
246 a.a.
223 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.3.4.21.4  - Trypsin.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
 Gene Ontology (GO) functional annotation 
  GO annot!
  Cellular component     extracellular region   2 terms 
  Biological process     digestion   2 terms 
  Biochemical function     protein binding     6 terms  

 

 

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