UniProt functional annotation for P46427

UniProt code: P46427.

Organism: Onchocerca volvulus.
Taxonomy: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida; Filarioidea; Onchocercidae; Onchocerca.
 
Function: Appears to play a central role in the parasite detoxification system.
 
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Subunit: Homodimer. {ECO:0000269|PubMed:15640152}.
Tissue specificity: Hypodermis, wall of the seminal receptacle and spermatozoa of adult worms.
Similarity: Belongs to the GST superfamily. Pi family. {ECO:0000305}.
Similarity: Contains 1 GST C-terminal domain. {ECO:0000305}.
Similarity: Contains 1 GST N-terminal domain. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.