UniProt functional annotation for P13272

UniProt code: P13272.

Organism: Bos taurus (Bovine).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos.
 
Function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
Function: The transit peptide of the Rieske protein seems to form part of the bc1 complex and is considered to be the subunit 11/IX of that complex.
 
Catalytic activity: Quinol + 2 ferricytochrome c = quinone + 2 ferrocytochrome c + 2 H(+).
Cofactor: Binds 1 2Fe-2S cluster per subunit.
Subunit: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).
Subcellular location: Mitochondrion inner membrane; Single-pass membrane protein.
Miscellaneous: The Rieske protein is a high potential 2Fe-2S protein.
Similarity: Contains 1 Rieske domain.
Sequence caution: Sequence=AAA30515.1; Type=Frameshift; Positions=Several;

Annotations taken from UniProtKB at the EBI.