UniProt functional annotation for P23827

UniProt code: P23827.

Organism: Escherichia coli (strain K12).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.
 
Function: General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. The strength of inhibition does not appear to be correlated with a particular protease specificity.
 
Subunit: Homodimer.
Subcellular location: Periplasm.
Similarity: Belongs to the protease inhibitor I11 (ecotin) family. {ECO:0000305}.
Sequence caution: Sequence=AAA16410.1; Type=Erroneous initiation; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.