|
|
||
|
|
|
|
|
UniProt functional annotation for P00757 | ||
|
|
|
|
|
|
||
| UniProt code: P00757. |
|
||
| Organism: | |
Mus musculus (Mouse). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus. |
|
||
| Cofactor: | |
Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 2 Zn(2+) ions per 7S complex. The Zn(2+) ions are bound at the alpha-gamma interfaces.; |
| Subunit: | |
7S nerve growth factor is composed of two alpha chains, a beta dimer composed of identical chains, and two gamma chains. |
| Ptm: | |
The presence of Gln-24 prevents cleavage of the activation peptide, which remains attached at the amino end of the mature alpha chain. |
| Similarity: | |
Belongs to the peptidase S1 family. Kallikrein subfamily. {ECO:0000255|PROSITE-ProRule:PRU00274}. |
Annotations taken from UniProtKB at the EBI.