| UniProt functional annotation for P0A333 | |||
| UniProt codes: P0A333, Q54397. |
| Organism: | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145). | |
| Taxonomy: | Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group. | |
| Function: | Acts as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel. {ECO:0000250}. | |
| Subunit: | Homotetramer. {ECO:0000250}. | |
| Subcellular location: | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. | |
| Domain: | The cytoplasmic C-terminus is involved in the gating mechanism. {ECO:0000250}. | |
| Miscellaneous: | The amino acids 62-79 are situated in the membrane and are important for channel structure and properties. {ECO:0000250}. | |
| Similarity: | Belongs to the potassium channel family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.