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PDBsum entry 1rus

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Lyase(carbon-carbon) PDB id
1rus
Jmol
Contents
Protein chains
437 a.a. *
Ligands
3PG ×2
* Residue conservation analysis

References listed in PDB file
Key reference
Title Crystal structure of the binary complex of ribulose-1,5-Bisphosphate carboxylase and its product, 3-Phospho-D-Glycerate.
Authors T.Lundqvist, G.Schneider.
Ref. J Biol Chem, 1989, 264, 3643-3646.
PubMed id 2492987
Abstract
The crystal structure of the binary complex of non-activated ribulose-1,5-bisphosphate carboxylase/oxygenase from Rhodospirillum rubrum and its product 3-phospho-D-glycerate has been determined to 2.9-A resolution. This structure determination confirms the proposed location of the active site (Schneider, G., Lindqvist, Y., Brändén, C.-I., and Lorimer, G. (1986) EMBO J. 5, 3409-3415) at the carboxyl end of the beta-strands of the alpha/beta-barrel in the carboxyl-terminal domain. One molecule of 3-phosphoglycerate is bound per active site. All oxygen atoms of 3-phosphoglycerate form hydrogen bonds to groups of the enzyme. The phosphate group interacts with the sidechains of residues Arg-288, His-321, and Ser-368, which are conserved between enzymes from different species as well as with the main chain nitrogens from residues Thr-322 and Gly-323. These amino acid residues constitute one of the two phosphate binding sites of the active site. The carboxyl group interacts with the side chains of His-287, Lys-191, and Asn-111. Implications of the activation process for the binding of 3-phosphoglycerate are discussed.
Secondary reference #1
Title Crystal structure of the binary complex of ribulose-1,5-Bisphosphate carboxylase and its product, 3-Phospho-D-Glycerate.
Authors T.Lundqvist, G.Schneider.
Ref. J Biol Chem, 1989, 264, 3643-3646.
PubMed id 2492987
Abstract
Secondary reference #2
Title Crystallographic refinement and structure of ribulose-1,5-Bisphosphate carboxylase from rhodospirillum rubrum at 1.7 angstroms resolution
Authors G.Schneider, Y.Lindqvist, T.Lundqvist.
Ref. j.mol.biol., 1990, 211, 989.
Secondary reference #3
Title Crystal structure of the complex of ribulose-1,5-Bisphosphate carboxylase and a transition state analogue, 2-Carboxy-D-Arabinitol 1,5-Bisphosphate.
Authors T.Lundqvist, G.Schneider.
Ref. J Biol Chem, 1989, 264, 7078-7083.
PubMed id 2708355
Abstract
Secondary reference #4
Title Crystal structure of the active site of ribulose-Bisphosphate carboxylase
Authors I.Andersson, S.Knight, G.Schneider, Y.Lindqvist, T.Lundqvist, C.-I.Branden, G.H.Lorimer.
Ref. nature, 1989, 337, 229.
Secondary reference #5
Title Three-Dimensional structure of ribulose-1,5-Bisphosphate carboxylase(slash)oxygenase from rhodospirillum rubrum at 2.9 angstroms resolution
Authors G.Schneider, Y.Lindqvist, C.-I.Branden, G.Lorimer.
Ref. embo j., 1986, 5, 3409.
PROCHECK
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 Headers