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PDBsum entry 1qrk

Go to PDB code: 
Top Page protein metals Protein-protein interface(s) links
Protein chain A    -    representing identical chain: B PDB id
1qrk
Protein chain A highlighted
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Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
11 sheets
1 beta alpha beta unit
14 beta hairpins
20 beta bulges
40 strands
15 helices
12 helix-helix interacs
60 beta turns
8 gamma turns
Catalytic residues
D396-C314-H373-Y560
Active sites
CAT
INA
Variants
Gly592Ser
Tyr204Phe
Phe53Ile
Thr550Ile
Leu588Gln
Ala132Ser
Glu651Gln
Ala394Val
Val650Ile
Arg684Gln
  
Chain & (700 residues)

UniProt code: P00488 (F13A_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (4 domains) :
Domain Links CATH no.   Class Architecture
1 2.60.40.10 = Mainly Beta Sandwich
2 3.90.260.10 = Alpha Beta Alpha-Beta Complex
3 2.60.40.10 = Mainly Beta Sandwich
4 2.60.40.10 = Mainly Beta Sandwich

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to metal
PDB SITE records:   
 CAT  CBT  INA  INB  AC1
 AC2

Jmol
RasMol

FASTA
file
Domain 1
Topology diagram


Hera


Domain 2
Topology diagram


Hera


Domain 3
Topology diagram


Hera


Domain 4
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
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