|
|
||
|
|
|
|
|
UniProt functional annotation for Q7SIG7 | ||
|
|
|
|
|
|
||
| UniProt code: Q7SIG7. |
|
||
| Organism: | |
Desulfurococcus sp. (strain Tok). |
| Taxonomy: | |
Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Desulfurococcaceae; Desulfurococcus; unclassified Desulfurococcus. |
|
||
|
||
| Function: | |
Thermostable DNA polymerase. In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity. {ECO:0000269|PubMed:8663453}. |
|
||
| Catalytic activity: | |
Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7; Evidence={ECO:0000269|PubMed:8663453}; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:10545321}; Note=Binds 2 magnesium ions. {ECO:0000269|PubMed:10545321}; |
| Activity regulation: | |
DNA polymerase activity strongly inhibited by uracil-containing oligonucleotides. {ECO:0000269|PubMed:8663453}. |
| Similarity: | |
Belongs to the DNA polymerase type-B family. {ECO:0000255}. |
Annotations taken from UniProtKB at the EBI.