| UniProt functional annotation for P00864 | |||
| UniProt code: P00864. |
| Organism: | Escherichia coli (strain K12). | |
| Taxonomy: | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia. | |
| Function: | Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | |
| Catalytic activity: | Reaction=oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452, ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31; | |
| Cofactor: | Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; | |
| Activity regulation: | The enzyme has distinct binding sites for each of the allosteric effectors such as acetyl-CoA, fructose 1,6-bisphosphate, guanosine 3'-diphosphate 5'-diphosphate, long chain fatty acids, and L- aspartate. | |
| Subunit: | Homotetramer. | |
| Similarity: | Belongs to the PEPCase type 1 family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.