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Ligand clusters for UniProt code P28482

Ligand clusters for P28482: Mitogen-activated protein kinase 1 OS=Homo sapiens GN=MAPK1 PE=1 SV=3

Top 6 (of 39) ligand clusters
Cluster 1.
57 ligand types
77 ligands
Cluster 2.
4 ligand types
9 ligands
Cluster 3.
3 ligand types
4 ligands
Cluster 4.
3 ligand types
12 ligands
Cluster 5.
3 ligand types
9 ligands
Cluster 6.
3 ligand types
8 ligands
Representative protein: 3sa0A  
 

Structures

PDB   Schematic diagram
3sa0A    
5bvfA    
4zxtA    
4fv4A    
4fv9A    
 more ...

 

 Cluster 1 contains 57 ligand types (of which only 20 are listed. Click for all)

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Ligand Description


 
1. Ligand: F29 × 1
1-Allyl-5-(2-Phenylpyrazolo[1,5-A]pyridin-3-Yl)-1h- Pyrazolo[3,4-C]pyridazin-3-Amine
PDB code: 1wzy(A).


 
2. Ligand: 82A × 1
(S)-N-(1-(3-Chloro-4-Fluorophenyl)-2-Hydroxyethyl)-4- (4-(3-Chlorophenyl)-1h-Pyrazol-3-Yl)-1h-
Pyrrole-2- Carboxamide
PDB code: 2ojj(A).


 
3. Ligand: 19A × 1
N,N-Dimethyl-4-(4-Phenyl-1h-Pyrazol-3-Yl)-1h-Pyrrole- 2-Carboxamide
PDB code: 2ojg(A).


 
4. Ligand: 33A × 1
N-Benzyl-4-[4-(3-Chlorophenyl)-1h-Pyrazol-3-Yl]-1h- Pyrrole-2-Carboxamide
PDB code: 2oji(A).


 
5. Ligand: FRZ × 1
5-(2-Phenylpyrazolo[1,5-A]pyridin-3-Yl)-1h-Pyrazolo[3, 4-C]pyridazin-3-Amine
PDB code: 1tvo(A).


 
6. Ligand: SB2 × 1
4-[5-(4-Fluoro-Phenyl)-2-(4-Methanesulfinyl-Phenyl)- 3h-Imidazol-4-Yl]-Pyridine
PDB code: 1pme(A).


 
7. Ligand: EDO × 11
1,2-Ethanediol
PDB codes: 4fuy(A), 4fv0(A), 4fv1(A), 4fv2(A), 4fv3(A), 4fv7(A), 4g6o(A), 4qta(A), 4qte(A), 5k4i(A).


 
8. Ligand: ANP × 6
Phosphoaminophosphonic acid-Adenylate ester
PDB codes: 2y9q(A), 3tei(A), 4fmq(A), 4h3p(A), 4h3q(A), 4nif(B).


 
9. Ligand: SO4 × 4
Sulfate ion
PDB codes: 4fux(A), 4g6n(A), 4iz5(A), 5lck(A).


 
10. Ligand: IMD × 3
Imidazole
PDB codes: 4qp1(A), 4qp2(A), 4qp6(A).


 
11. Ligand: 1FM × 1
(3s,5z,8s,9s,11e)-8,9,16-Trihydroxy-14-Methoxy-3- Methyl-3,4,9,10-Tetrahydro-1h-2-
Benzoxacyclotetradecine-1,7(8h)-Dione
PDB code: 3w55(A).


 
12. Ligand: 2SH × 1
N-[(1s)-1-(3-Chloro-4-Fluorophenyl)-2-Hydroxyethyl]-2- (Tetrahydro-2h-Pyran-4-Ylamino)-5,8-
Dihydropyrido[3,4- D]pyrimidine-7(6h)-Carboxamide
PDB code: 4o6e(A).


 
13. Ligand: 35W × 1
7-(1-Benzyl-1h-Pyrazol-4-Yl)-2-(Pyridin-4-Yl)-5h- Pyrrolo[2,3-B]pyrazine
PDB code: 4qpa(A).


 
14. Ligand: 35X × 1
7-(1-Propyl-1h-Pyrazol-4-Yl)-2-(Pyridin-4-Yl)-5h- Pyrrolo[2,3-B]pyrazine
PDB code: 4qp9(A).


 
15. Ligand: 362 × 1
2-(1h-Pyrazol-4-Yl)-7-(Pyridin-3-Yl)-5h-Pyrrolo[2,3- B]pyrazine
PDB code: 4qp8(A).


 
16. Ligand: 363 × 1
2-(1h-Pyrazol-4-Yl)-5h-Pyrrolo[2,3-B]pyrazine
PDB code: 4qp7(A).


 
17. Ligand: 36N × 1
5h-Pyrrolo[2,3-B]pyrazine
PDB code: 4qp6(A).


 
18. Ligand: 36O × 1
N-Cyclohexyl-9h-Purin-6-Amine
PDB code: 4qp4(A).


 
19. Ligand: 36Q × 1
(2s)-3-Phenyl-2-(9h-Purin-6-Ylamino)propan-1-Ol
PDB code: 4qp3(A).


 
20. Ligand: 36R × 1
5-Chloro-1,3-Benzoxazol-2-Amine
PDB code: 4qp2(A).

 + more. Press for full list
 

 

 Cluster 2 contains 4 ligand types

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Ligand Description


 
1. Ligand: EDO × 6
1,2-Ethanediol
PDB codes: 4fv0(A), 4fv3(A), 4fv7(A), 4g6o(A), 4qte(A),


 
2. Ligand: GOL × 1
Glycerol
PDB code: 4fv2(A).


 
3. Ligand: PEG × 1
Di(hydroxyethyl)ether
PDB code: 4n0s(A).

_Ni
 
4. Metal: _NI × 1
PDB code: 5bue(A).

 

 Cluster 3 contains 3 ligand types

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Ligand Description


 
1. Ligand: EDO × 2
1,2-Ethanediol
PDB codes: 4fv0(A), 4fv2(A).


 
2. Ligand: GOL × 1
Glycerol
PDB code: 4fv7(A).


 
3. Ligand: SO4 × 1
Sulfate ion
PDB code: 4qte(A).

 

 Cluster 4 contains 3 ligand types

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Ligand Description


 
1. Ligand: EDO × 6
1,2-Ethanediol
PDB codes: 4fv5(A), 4fv6(A), 4fv7(A), 4fv8(A), 4fv9(A), 4qte(A).


 
2. Ligand: SO4 × 5
Sulfate ion
PDB codes: 4nif(B), 4qta(A), 5bvd(A), 5bve(A), 5bvf(A).


 
3. Ligand: GOL × 1
Glycerol
PDB code: 4fv4(A).

 

 Cluster 5 contains 3 ligand types

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Ligand Description


 
1. Ligand: DMS × 1
dimethyl sulfoxide
Dimethyl sulfoxide
PDB code: 4n0s(A).


 
2. Ligand: EDO × 6
1,2-Ethanediol
PDB codes: 4fv0(A), 4fv1(A), 4fv2(A), 4fv3(A), 4g6o(A), 4qte(A).


 
3. Ligand: SO4 × 2
Sulfate ion
PDB codes: 5lcj(A), 5lck(A).

 

 Cluster 6 contains 3 ligand types

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Ligand Description


 
1. Ligand: SO4 × 5
Sulfate ion
PDB codes: 3i5z(A), 4fv5(A), 4fv8(A), 4fv9(A), 4iz5(A).


 
2. Ligand: EDO × 2
1,2-Ethanediol
PDB codes: 4fv1(A), 4qte(A).

_Na
 
3. Metal: _NA × 1
PDB code: 4nif(B).

 

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