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UniProt functional annotation for P11927 | ||
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| UniProt code: P11927. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
KAR1 is required for function of both intranuclear and extranuclear microtubules. KAR1 helps localize CDC31 to the spindle pole body (SPB), CDC31 then initiates SPB duplication via interaction with a downstream effector. {ECO:0000269|PubMed:10428957, ECO:0000269|PubMed:7876310, ECO:0000269|PubMed:8070654}. |
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| Subunit: | |
Interacts with SPC72. {ECO:0000269|PubMed:10428957}. |
| Subcellular location: | |
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. |
Annotations taken from UniProtKB at the EBI.