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UniProt functional annotation for O76036 | ||
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| UniProt code: O76036. |
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| Organism: | |
Homo sapiens (Human). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. |
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| Function: | |
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. {ECO:0000269|PubMed:9730896}. |
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| Subunit: | |
Interacts with CD247 and FCER1G. {ECO:0000269|PubMed:9730896}. |
| Subcellular location: | |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue specificity: | |
Selectively expressed by both resting and activated NK cells. {ECO:0000269|PubMed:9730896}. |
| Ptm: | |
N-glycosylated. {ECO:0000269|PubMed:9730896}. |
| Ptm: | |
O-glycosylated. {ECO:0000269|PubMed:9730896}. |
| Similarity: | |
Belongs to the natural cytotoxicity receptor (NCR) family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.