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PDBsum entry 1o8a

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Protein chain A PDB id
1o8a
Protein chain A highlighted
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Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
3 sheets
2 beta hairpins
6 strands
32 helices
67 helix-helix interacs
29 beta turns
5 gamma turns
3 disulphides
Catalytic residues
E411-Y523
A354-E384-H353-H513-Y523-M701
Active sites
NG1
NG2
NG3
NG4
ACT
ZN1
NXA
CL1
CL2
Variants
Ile193Val
His410Gln
Thr311Met
Thr605Met
Asn431Lys
Pro497Thr
Met223Thr
Thr582Met
  
Chain (575 residues)

UniProt code: P12821 (ACE_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (1 domain) :
Domain Links CATH no.   Class Architecture
1 unassigned

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
Disulphides:   
    disulphide bond
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand     to metal
PDB SITE records:   
 AC1  AC2  AC3  AC4  AC5
 AC6  AC7  AC8  AC9  BC1
 BC2


FASTA
file
Domain 1
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
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