UniProt functional annotation for P13538

UniProt code: P13538.

Organism: Gallus gallus (Chicken).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Testudines + Archosauria group; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.
 
Function: Muscle contraction. Myosin is a protein that binds to F- actin and has ATPase activity that is activated by F-actin.
 
Subunit: Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2).
Subcellular location: Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Domain: The rodlike tail sequence is highly repetitive, showing cycles of a 28-residue repeat pattern composed of 4 heptapeptides, characteristic for alpha-helical coiled coils.
Domain: Each myosin heavy chain can be split into 1 light meromyosin (LMM) and 1 heavy meromyosin (HMM). It can later be split further into 2 globular subfragments (S1) and 1 rod-shaped subfragment (S2).
Similarity: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Similarity: Contains 1 IQ domain.
Similarity: Contains 1 myosin motor domain.

Annotations taken from UniProtKB at the EBI.