spacer
spacer

PDBsum entry 1o04

Go to PDB code: 
Top Page protein ligands metals Protein-protein interface(s) links
Protein chain A    -    representing identical chains: B C D E F G H PDB id
1o04
Protein chain A highlighted
(click to view)
 
Jmol
Motifs
Secondary structure
Wiring diagram
Residue conservation
ProMotif
5 sheets
6 beta alpha beta units
4 beta hairpins
4 beta bulges
20 strands
19 helices
31 helix-helix interacs
24 beta turns
8 gamma turns
Catalytic residues
M6505-E268A-E399A-K192A-S302A
Variants
Ile24Val
Asp282Asn
PROSITE
ALDEHYDE_D
EHYDR_GLU
  
Chain & (494 residues)

UniProt code: P05091 (ALDH2_HUMAN)   [Pfam]   [Ensembl gene]

structural classification (2 domains) :
Domain Links CATH no.   Class Architecture
1 3.40.605.10 = Alpha Beta 3-Layer(aba) Sandwich
2 3.40.309.10 = Alpha Beta 3-Layer(aba) Sandwich

Key:  
Sec. struc: Helices labelled H1, H2, ... and strands by their sheets A, B, ...
  Helix Strand  
Motifs:   
    beta turn     gamma turn     beta hairpin
CSA annotation:   
    catalytic residue
Human variant:   
    variant residue
Residue contacts:   
    to ligand     to metal
PDB SITE records:   
 AC1  AC2  AC3  AC4  AC5
 AC6  AC7  AC8  AC9  BC1
 BC2  BC3  BC4  BC5  BC6
 BC7  BC8  BC9  CC1  CC2
 CC3  CC4  CC5  CC6  CC7
 CC8  CC9  DC1  DC2  DC3
 DC4  DC5  DC6  DC7  DC8
 DC9  EC1  EC2  EC3  EC4
 EC5  EC6  EC7  EC8  EC9
 FC1  FC2  FC3  FC4  FC5
 FC6  FC7  FC8  FC9  GC1
 GC2  GC3  GC4  GC5  GC6
 GC7  GC8  GC9  HC1  HC2
 HC3  HC4  HC5  HC6  HC7
 HC8  HC9  IC1  IC2

Jmol
RasMol

FASTA
file
Domain 1
Topology diagram


Hera


Domain 2
Topology diagram


Hera


  Analysis of sequence's residue conservation
  Related protein sequences in the PDB
  
spacer
spacer