| UniProt functional annotation for Q7A189 | |||
| UniProt code: Q7A189. |
| Organism: | Staphylococcus aureus (strain MW2). | |
| Taxonomy: | Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus. | |
| Function: | Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology (By similarity). {ECO:0000250}. | |
| Subunit: | Forms a stable non-covalent complex with prematurely activated/folded SspB. {ECO:0000250}. | |
| Subcellular location: | Cytoplasm {ECO:0000250}. | |
| Domain: | N-terminal residues are not required for inhibitory activity. | |
| Miscellaneous: | Inactivated by staphylococcal serine protease (SspA). {ECO:0000250}. | |
| Similarity: | Belongs to the protease inhibitor I57 (SspC) family. {ECO:0000305}. | |
Annotations taken from UniProtKB at the EBI.