UniProt functional annotation for Q7A189

UniProt code: Q7A189.

Organism: Staphylococcus aureus (strain MW2).
Taxonomy: Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae; Staphylococcus.
 
Function: Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology (By similarity). {ECO:0000250}.
 
Subunit: Forms a stable non-covalent complex with prematurely activated/folded SspB. {ECO:0000250}.
Subcellular location: Cytoplasm {ECO:0000250}.
Domain: N-terminal residues are not required for inhibitory activity.
Miscellaneous: Inactivated by staphylococcal serine protease (SspA). {ECO:0000250}.
Similarity: Belongs to the protease inhibitor I57 (SspC) family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.