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PDBsum entry 1n0x

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protein ligands metals Protein-protein interface(s) links
Immune system PDB id
1n0x

 

 

 

 

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Contents
Protein chains
215 a.a. *
222 a.a. *
21 a.a. *
20 a.a. *
Ligands
GOL ×8
SO4 ×4
CXS
Metals
__K
Waters ×725
* Residue conservation analysis
PDB id:
1n0x
Name: Immune system
Title: Crystal structure of a broadly neutralizing anti-HIV-1 antibody in complex with a peptide mimotope
Structure: Immunoglobulin light chain. Chain: l, m. Fragment: unp residues 132-239. Synonym: igg. Engineered: yes. Immunoglobulin heavy chain. Chain: h, k. Fragment: unp residues 117-222. Synonym: igg,immunoglobulin gamma-1 heavy chain nie.
Source: Homo sapiens. Human, human. Organism_taxid: 9606. Expressed in: cricetulus griseus. Expression_system_taxid: 10029. Expression_system_cell: ovary cells. Synthetic: yes. Synthetic construct. Organism_taxid: 32630.
Biol. unit: Hexamer (from PQS)
Resolution:
1.80Å     R-factor:   0.220     R-free:   0.252
Authors: E.O.Saphire,M.Montero,A.Menendez,M.B.Irving,M.B.Zwick,P.W.H.I.Parren, D.R.Burton,J.K.Scott,I.A.Wilson
Key ref: E.O.Saphire et al. Crystal structure of a broadly neutralizing anti-Hiv-1 antibody in complex with a peptide mimotope. To be published, .
Date:
15-Oct-02     Release date:   13-Apr-04    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
Pfam   ArchSchema ?
P01834  (IGKC_HUMAN) -  Immunoglobulin kappa constant from Homo sapiens
Seq:
Struc:
107 a.a.
215 a.a.*
Protein chains
Pfam   ArchSchema ?
P0DOX5  (IGG1_HUMAN) -  Immunoglobulin gamma-1 heavy chain from Homo sapiens
Seq:
Struc:
449 a.a.
222 a.a.*
Protein chain
No UniProt id for this chain
Struc: 21 a.a.
Protein chain
No UniProt id for this chain
Struc: 20 a.a.
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 66 residue positions (black crosses)

 

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