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UniProt functional annotation for P54784 | ||
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| UniProt code: P54784. |
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| Organism: | |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). |
| Taxonomy: | |
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. |
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| Function: | |
Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication. {ECO:0000269|PubMed:17825064}. |
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| Subunit: | |
Component of the origin recognition complex (ORC) composed of at least ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. Interacts with MCM10 and TAH11. {ECO:0000269|PubMed:11168584, ECO:0000269|PubMed:17825064}. |
| Subcellular location: | |
Nucleus. |
| Domain: | |
The N-terminus is dedicated to mating-type repression. |
| Miscellaneous: | |
Present with 3930 molecules/cell in log phase SD medium. {ECO:0000269|PubMed:14562106}. |
| Similarity: | |
Belongs to the ORC1 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.