UniProt functional annotation for P32503



	UniProt functional annotation for P32503

UniProt code: P32503.

Organism: Saccharomyces cerevisiae virus L-A (ScV-L-A) (ScVL1).

Taxonomy: Viruses; Riboviria; Orthornavirae; Duplornaviricota; Chrymotiviricetes; Ghabrivirales; Totiviridae; Totivirus.

Function: Capsid protein self-assembles to form an icosahedral capsid with a T=2 symmetry, 40 nm in diameter, and consisting of 60 capsid proteins asymmetric dimers. The capsid encapsulates the genomic dsRNA and the polymerase and remains intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of the virion and are extruded into the cytoplasm.

Function: Binds and removes 5' cap structures from cellular mRNA. Forms a covalent bond with m7GMP through His-154 of the capsid protein while releasing the mRNA body.

Subcellular location: Virion {ECO:0000305}.

Ptm: Acetylation is necessary for viral assembly. {ECO:0000269|PubMed:1400344}.

Miscellaneous: [Isoform Major capsid protein]: Produced by conventional translation.

Similarity: Belongs to the totivirus major capsid protein family. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.


Organism:		Saccharomyces cerevisiae virus L-A (ScV-L-A) (ScVL1).
Taxonomy:		Viruses; Riboviria; Orthornavirae; Duplornaviricota; Chrymotiviricetes; Ghabrivirales; Totiviridae; Totivirus.



Function:		Capsid protein self-assembles to form an icosahedral capsid with a T=2 symmetry, 40 nm in diameter, and consisting of 60 capsid proteins asymmetric dimers. The capsid encapsulates the genomic dsRNA and the polymerase and remains intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of the virion and are extruded into the cytoplasm.



Function:		Binds and removes 5' cap structures from cellular mRNA. Forms a covalent bond with m7GMP through His-154 of the capsid protein while releasing the mRNA body.


Subcellular location:		Virion {ECO:0000305}.
Ptm:		Acetylation is necessary for viral assembly. {ECO:0000269\|PubMed:1400344}.
Miscellaneous:		[Isoform Major capsid protein]: Produced by conventional translation.
Similarity:		Belongs to the totivirus major capsid protein family. {ECO:0000305}.