UniProt functional annotation for Q9I4K6

UniProt code: Q9I4K6.

Organism: Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas.
 
Function: Metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin.
 
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Cofactor: Manganese.
Enzyme regulation: Requires the monovalent cation K(+) for optimal activity.
Subunit: Homodimer (By similarity).
Subcellular location: Cytoplasm (By similarity).
Similarity: Belongs to the fosfomycin resistance protein family.

Annotations taken from UniProtKB at the EBI.