UniProt functional annotation for P03023



	UniProt functional annotation for P03023

UniProt code: P03023.

Organism: Escherichia coli (strain K12).

Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.

Function: Repressor of the lactose operon. Binds allolactose as an inducer.

Subunit: Homotetramer.

Miscellaneous: Removing residues 1-59 results in loss of DNA-binding activity but retains tetrameric structure and inducer-binding activity. Deleting residues 340-360 results in loss of tetramer formation, but retains dimer formation, inducer-binding activity, and DNA-binding activity (if residues 1-59 are present).

Sequence caution: Sequence=AAB18069.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAB47270.1; Type=Erroneous initiation; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.


Organism:		Escherichia coli (strain K12).
Taxonomy:		Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia.



Function:		Repressor of the lactose operon. Binds allolactose as an inducer.


Subunit:		Homotetramer.
Miscellaneous:		Removing residues 1-59 results in loss of DNA-binding activity but retains tetrameric structure and inducer-binding activity. Deleting residues 340-360 results in loss of tetramer formation, but retains dimer formation, inducer-binding activity, and DNA-binding activity (if residues 1-59 are present).
Sequence caution:		Sequence=AAB18069.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAB47270.1; Type=Erroneous initiation; Evidence={ECO:0000305};