UniProt functional annotation for P33148



	UniProt functional annotation for P33148

UniProt code: P33148.

Organism: Xenopus laevis (African clawed frog).

Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.

Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subunit: Interacts with CTNNB1. {ECO:0000269|PubMed:17052462}.

Subcellular location: Cell membrane; Single-pass type I membrane protein.

Developmental stage: Unfertilized eggs and early Xenopus embryos.

Domain: Three calcium ions are usually bound at the interface of each cadherin domain.

Sequence caution: Sequence=CAA45252.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};

Annotations taken from UniProtKB at the EBI.


Organism:		Xenopus laevis (African clawed frog).
Taxonomy:		Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.



Function:		Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.


Subunit:		Interacts with CTNNB1. {ECO:0000269\|PubMed:17052462}.
Subcellular location:		Cell membrane; Single-pass type I membrane protein.
Developmental stage:		Unfertilized eggs and early Xenopus embryos.
Domain:		Three calcium ions are usually bound at the interface of each cadherin domain.
Sequence caution:		Sequence=CAA45252.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};