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UniProt functional annotation for O26249 | ||
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| UniProt code: O26249. |
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| Organism: | |
Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum). |
| Taxonomy: | |
Archaea; Euryarchaeota; Methanomada group; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter. |
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| Function: | |
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7. {ECO:0000305|PubMed:12429089}. |
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| Catalytic activity: | |
Reaction=Co-precorrin-6B + S-adenosyl-L-methionine = Co-precorrin-7 + CO2 + S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:36067, ChEBI:CHEBI:16526, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:70791, ChEBI:CHEBI:72780; EC=2.1.1.196; Evidence={ECO:0000255|HAMAP-Rule:MF_00786}; |
| Pathway: | |
Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 8/10. {ECO:0000255|HAMAP-Rule:MF_00786}. |
| Subunit: | |
Homotetramer. {ECO:0000269|PubMed:12429089}. |
| Similarity: | |
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family. {ECO:0000255|HAMAP-Rule:MF_00786}. |
Annotations taken from UniProtKB at the EBI.