UniProt functional annotation for P08048

UniProt code: P08048.

Organism: Homo sapiens (Human).
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
 
Function: Probable transcriptional activator. Binds to the consensus sequence 5'-AGGCCY-3'. {ECO:0000269|PubMed:20028140}.
 
Subcellular location: Nucleus.
Domain: The binding of ZFY to DNA is mediated by the interaction of the GGCC core base pairs with zinc fingers 12 and 13. {ECO:0000269|PubMed:20028140}.
Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. {ECO:0000305}.

Annotations taken from UniProtKB at the EBI.