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UniProt functional annotation for O66145 | ||
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| UniProt code: O66145. |
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| Organism: | |
Citrobacter amalonaticus. |
| Taxonomy: | |
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Citrobacter. |
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| Function: | |
Involved in the methylaspartate cycle. Catalyzes the formation of the alpha,beta-unsaturated bond by the reversible anti elimination of ammonia from L-threo-beta-methylaspartate (L-threo- (2S,3S)-3-methylaspartate) to give mesaconate (By similarity). {ECO:0000250}. |
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| Catalytic activity: | |
Reaction=(2S,3S)-3-methyl-L-aspartate = mesaconate + NH4(+); Xref=Rhea:RHEA:12829, ChEBI:CHEBI:28938, ChEBI:CHEBI:36986, ChEBI:CHEBI:58724; EC=4.3.1.2; |
| Cofactor: | |
Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:11796115}; |
| Pathway: | |
Amino-acid degradation; L-glutamate degradation via mesaconate pathway; acetate and pyruvate from L-glutamate: step 2/4. |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:11796115}. |
| Similarity: | |
Belongs to the methylaspartate ammonia-lyase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.