UniProt functional annotation for P00929

UniProt code: P00929.

Organism: Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
Taxonomy: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
 
Function: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate.
 
Catalytic activity: L-serine + 1-C-(indol-3-yl)glycerol 3- phosphate = L-tryptophan + D-glyceraldehyde 3-phosphate + H(2)O. {ECO:0000255|HAMAP-Rule:MF_00131}.
Pathway: Amino-acid biosynthesis; L-tryptophan biosynthesis; L- tryptophan from chorismate: step 5/5. {ECO:0000255|HAMAP- Rule:MF_00131}.
Subunit: Tetramer of two alpha and two beta chains.
Similarity: Belongs to the TrpA family. {ECO:0000255|HAMAP- Rule:MF_00131}.

Annotations taken from UniProtKB at the EBI.