PDBsum entry 1k73

Tunnel analysis for: 1k73 calculated with

MOLE 2.0

PDB id

1k73

Tunnels calculated on whole structure

Tunnels calculated excluding ligands

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without HETATM:

5 tunnels, coloured by tunnel radius

34 tunnels, coloured by tunnel radius

34 tunnels, coloured as in
list below

Tunnels are interior spaces connected with the protein surrounding. Only channels longer than 15 Å are shown.

Tunnels

Free R

Length

HPathy

HPhob

Polar

Rel Mut

Residue..type

Ligands

Radius

1.38

78.1

-0.42

-0.80

3.4

G 13 A C 14 A G 531 A C 534 A G 535 A C 613 A A
629 A A 630 A A 631 A A 1367 A G 2058 A U 2059 A
A 2060 A C 2061 A A 2062 A U 2063 A C 2071 A G
2072 A G 2073 A A 2074 A G 2075 A U 2076 A A 2095
A A 2096 A A 2488 A G 2489 A C 2534 A U 2539 A U
2650 A C 2651 A NA 8305 A

1.35

80.9

-0.63

-0.81

4.4

A 11 A U 12 A G 13 A C 14 A C 523 A A 524 A G 525
A U 526 A A 629 A A 630 A A 631 A A 1367 A G 2058
A U 2059 A A 2060 A C 2061 A A 2062 A C 2071 A G
2072 A G 2073 A A 2074 A G 2075 A U 2076 A A 2095
A A 2096 A A 2488 A G 2489 A C 2534 A U 2539 A U
2650 A C 2651 A NA 8305 A

1.33

95.9

-0.48

-0.80

4.5

C 14 A C 15 A A 16 A G 17 A C 18 A U 19 A G 20 A
U 510 A A 519 A A 520 A U 522 A C 523 A A 629 A A
630 A A 631 A A 1337 A U 1338 A C 1366 A A 1367 A
G 2058 A U 2059 A A 2060 A C 2061 A A 2062 A C
2071 A G 2072 A G 2073 A A 2074 A G 2075 A U 2076
A A 2095 A A 2096 A A 2488 A G 2489 A C 2534 A U
2539 A U 2650 A NA 8305 A

1.34

113.3

-0.60

-0.78

5.9

G 13 A C 14 A A 629 A A 630 A A 631 A A 1367 A G
2058 A U 2059 A A 2060 A C 2061 A A 2062 A U 2063
A C 2071 A G 2072 A G 2073 A A 2074 A G 2075 A U
2076 A C 2084 A A 2085 A C 2086 A C 2087 A A 2095
A A 2096 A A 2488 A G 2489 A C 2534 A U 2539 A U
2650 A C 2651 A U 2652 A A 2653 A C 2654 A U 2655
A G 2657 A G 2658 A U 2659 A A 2664 A G 2667 A G
2668 A U 2669 A G 2670 A U 2671 A A 2811 A A 2812
A A 2818 A C 2819 A C 2844 A NA 8305 A

1.38

113.5

-0.67

-0.77

6.6

A 16 A G 17 A U 522 A A 629 A A 630 A A 631 A G
1302 A C 1303 A G 1319 A U 1320 A A 1321 A G 1322
A A 1331 A C 1332 A U 1333 A A 1345 A U 1346 A A
1367 A G 2058 A U 2059 A A 2060 A C 2061 A A 2062
A C 2071 A G 2072 A G 2073 A A 2074 A G 2075 A U
2076 A A 2095 A A 2096 A A 2488 A G 2489 A C 2534
A U 2539 A U 2650 A NA 8305 A MG 8109 Z

1.33

113.6

-0.44

-0.72

4.7

A 629 A A 630 A A 631 A C 633 A G 634 A A 635 A U
845 A U 1359 A C 2056 A U 2057 A G 2058 A U 2059
A C 2071 A G 2072 A G 2073 A A 2074 A G 2075 A U
2076 A A 2096 A C 2098 A G 2099 A A 2100 A A 2103
A A 2486 A C 2487 A A 2488 A G 2489 A U 2528 A C
2534 A U 2539 A G 2540 A U 2541 A C 2542 A C 2608
A U 2619 A U 2620 A A 2637 A C 2644 A NA 8305 A N
A 8363 A ANM 9000 A

1.32

116.1

-0.67

-0.76

6.7

101

A 16 A G 17 A U 522 A A 629 A A 630 A A 631 A G
1316 A A 1317 A A 1318 A G 1319 A U 1320 A A 1321
A G 1322 A G 1323 A U 1333 A C 1334 A C 1335 A U
1336 A A 1337 A U 1338 A G 1339 A A 1367 A G 2058
A U 2059 A A 2060 A C 2061 A A 2062 A C 2071 A G
2072 A G 2073 A A 2074 A G 2075 A U 2076 A A 2095
A A 2096 A A 2488 A G 2489 A C 2534 A U 2539 A U
2650 A NA 8305 A MG 8109 Z

1.24

1.45

118.3

-0.83

-0.65

10.4

C 764 A G 765 A A 766 A U 768 A C 769 A C 770 A G
771 A G 772 A A 773 A U 866 A A 867 A G 868 A G
869 A G 887 A U 888 A C 889 A C 890 A A 895 A C
896 A A 897 A U 1359 A C 1360 A C 1361 A A 1459 A
G 1460 A U 1461 A C 1474 A G 1475 A A 1476 A C
1477 A U 1478 A A 1479 A C 1862 A G 1863 A C 1864
A A 1869 A C 1872 A A 2101 A A 2479 A G 2480 A

1.22

1.21

117.7

-0.65

-0.79

5.1

G 13 A C 14 A U 468 A G 531 A C 534 A G 535 A C
613 A A 631 A C 633 A G 634 A A 635 A G 636 A C
842 A A 843 A A 844 A A 882 A U 1359 A G 1363 A A
1367 A G 1688 A A 1689 A C 1692 A A 1693 A G 1694
A C 2056 A U 2057 A G 2058 A U 2059 A A 2060 A C
2061 A A 2062 A U 2063 A G 2075 A A 2095 A A 2096
A C 2098 A G 2099 A A 2100 A U 2650 A C 2651 A MG
8063 A NA 8363 A

1.28

1.44

120.6

-0.53

-0.64

6.3

U 624 A U 625 A U 626 A A 628 A A 632 A C 633 A G
634 A C 764 A G 765 A G 901 A G 956 A A 957 A G
958 A U 1003 A C 1044 A G 1046 A U 1047 A G 1048
A C 1049 A G 1050 A C 1051 A G 1052 A C 1060 A C
1061 A U 1062 A A 1358 A U 1359 A C 1360 A C 1361
A A 2101 A G 2481 A G 2482 A A 2483 A C 2533 A U
2535 A G 2537 A NA 8350 A NA 8352 A A 3077 B U
3079 B A 3080 B C 3081 B A 3093 B G 3094 B C 3095
B A 3105 B

1.38

119.5

-1.21

-0.77

11.8

A 466 A G 467 A A 476 A A 497 A A 498 A G 499 A A
513 A G 514 A A 629 A A 630 A A 631 A C 633 A G
634 A A 635 A G 636 A U 1359 A G 1363 A A 1427 A
C 1428 A G 1441 A C 2056 A U 2057 A G 2058 A U
2059 A C 2071 A G 2072 A G 2073 A A 2074 A G 2075
A U 2076 A A 2096 A C 2098 A G 2099 A A 2100 A A
2488 A G 2489 A C 2534 A U 2539 A MG 8063 A NA
8305 A NA 8363 A

1.35

119.5

-0.68

-0.80

5.6

A 629 A A 630 A A 631 A G 1119 A U 1120 A C 1129
A U 1130 A C 1228 A A 1231 A A 1232 A A 1233 A U
1234 A A 1236 A U 1237 A C 1238 A U 2059 A A 2060
A C 2061 A A 2062 A C 2065 A C 2066 A G 2068 A U
2069 A C 2071 A G 2072 A G 2073 A A 2074 A G 2075
A U 2076 A G 2094 A A 2095 A A 2096 A A 2488 A G
2489 A A 2490 A G 2491 A G 2524 A G 2525 A C 2534
A U 2539 A A 2776 A G 2777 A A 2792 A NA 8305 A

1.28

1.42

133.9

-0.68

-0.61

7.5

U 651 A G 652 A U 701 A G 702 A G 703 A C 704 A G
720 A A 721 A G 722 A G 723 A G 724 A C 725 A G
742 A G 743 A G 744 A A 756 A C 757 A A 761 A C
762 A C 763 A C 764 A G 765 A A 766 A A 895 A C
896 A A 897 A A 926 A U 927 A G 1036 A G 1037 A G
1038 A G 1039 A A 1040 A U 1359 A C 1360 A C 1361
A A 2101 A A 2479 A G 2480 A

1.24

1.45

133.7

-0.84

-0.69

10.9

U 214 A U 651 A G 652 A G 661 A G 681 A A 682 A G
683 A G 684 A C 685 A A 686 A C 687 A G 689 A G
690 A G 691 A G 742 A A 756 A C 757 A A 761 A C
762 A C 763 A C 764 A G 765 A A 766 A A 895 A C
896 A A 897 A A 926 A U 927 A G 1038 A G 1039 A A
1040 A U 1359 A C 1360 A C 1361 A A 2101 A A 2479
A G 2480 A NA 8341 A

1.22

1.37

132.6

-0.95

-0.66

9.1

C 764 A G 765 A A 766 A U 768 A C 769 A C 770 A G
771 A G 772 A A 773 A G 868 A G 869 A G 887 A U
888 A C 889 A C 890 A A 895 A C 896 A A 897 A U
1359 A C 1360 A C 1361 A C 1474 A G 1863 A C 1864
A A 1865 A A 1909 A A 2101 A G 2121 A C 2122 A A
2123 A G 2124 A G 2125 A C 2126 A G 2263 A U 2265
A A 2266 A G 2267 A C 2268 A G 2270 A A 2479 A G
2480 A

1.24

1.45

138.9

-0.39

-0.70

4.7

U 624 A U 625 A U 626 A A 628 A A 632 A C 633 A G
634 A C 764 A G 765 A G 901 A A 913 A A 914 A C
915 A A 929 A C 930 A A 943 A G 944 A U 945 A C
946 A U 947 A C 1015 A U 1017 A A 1018 A C 1019 A
C 1044 A G 1045 A G 1046 A U 1062 A G 1063 A U
1064 A G 1065 A U 1066 A A 1358 A U 1359 A C 1360
A C 1361 A A 2101 A C 2393 A G 2481 A G 2482 A A
2483 A C 2533 A U 2535 A G 2537 A NA 8350 A G
3100 B G 3101 B

1.24

1.45

143.8

-0.94

-0.58

12.9

A 466 A G 467 A U 468 A A 476 A U 488 A G 500 A G
501 A A 502 A G 503 A A 509 A U 510 A G 512 A A
513 A G 514 A C 764 A G 765 A A 766 A A 767 A U
768 A A 844 A A 882 A U 883 A U 888 A C 889 A A
895 A C 896 A A 897 A U 1359 A C 1360 A C 1361 A
A 1427 A C 1428 A A 1689 A A 2101 A A 2479 A G
2480 A

1.32

151.9

-0.60

-0.79

5.9

G 13 A C 14 A A 629 A A 630 A A 631 A G 1235 A A
1367 A G 2058 A U 2059 A A 2060 A C 2061 A A 2062
A U 2063 A C 2071 A G 2072 A G 2073 A A 2074 A G
2075 A U 2076 A A 2083 A C 2084 A A 2085 A C 2086
A C 2087 A A 2095 A A 2096 A A 2488 A G 2489 A C
2534 A U 2539 A U 2550 A U 2650 A C 2651 A U 2652
A A 2653 A C 2654 A U 2655 A G 2657 A A 2677 A A
2678 A G 2679 A A 2680 A A 2681 A U 2705 A A 2706
A C 2769 A G 2770 A G 2771 A G 2798 A A 2799 A A
2800 A A 2801 A C 2802 A C 2803 A C 2804 A A 2805
A G 2809 A A 2812 A A 2813 A NA 8305 A

1.36

154.9

-0.40

-0.72

4.3

A 629 A A 630 A A 631 A C 633 A G 634 A A 635 A U
825 A G 828 A G 830 A U 831 A C 839 A U 845 A A
846 A C 847 A C 848 A C 849 A U 850 A U 1359 A G
1378 A A 1379 A A 1407 A A 1712 A G 1713 A G 1739
A G 1756 A U 1757 A U 1758 A A 1759 A C 1816 A U
1817 A C 1818 A G 1837 A U 1838 A C 2056 A U 2057
A G 2058 A U 2059 A C 2071 A G 2072 A G 2073 A A
2074 A G 2075 A U 2076 A A 2096 A C 2098 A G 2099
A A 2100 A A 2488 A G 2489 A C 2534 A U 2539 A C
2644 A U 2645 A G 2646 A C 2752 A G 2753 A MG
8071 A NA 8305 A NA 8363 A NA 8379 A

1.32

161.6

-0.82

-0.75

8.4

A 629 A A 630 A A 631 A C 633 A G 634 A A 635 A A
767 A U 768 A C 769 A C 770 A G 771 A G 772 A A
773 A A 844 A U 845 A U 866 A A 867 A G 868 A G
869 A U 883 A C 884 A G 887 A U 888 A C 889 A C
890 A U 1359 A A 1458 A A 1459 A G 1460 A U 1461
A C 1474 A G 1475 A A 1476 A C 1477 A U 1478 A A
1479 A U 1480 A G 1481 A A 1482 A G 1837 A C 1862
A G 1863 A C 1864 A C 2056 A U 2057 A G 2058 A U
2059 A C 2071 A G 2072 A G 2073 A A 2074 A G 2075
A U 2076 A A 2096 A C 2098 A G 2099 A A 2100 A U
2478 A A 2488 A G 2489 A C 2534 A U 2539 A NA
8305 A NA 8363 A

1.35

169.2

-0.76

-0.72

8.9

U 133 A U 134 A A 629 A A 630 A A 631 A C 633 A G
634 A A 635 A A 767 A U 768 A C 769 A C 770 A G
771 A G 772 A A 773 A C 774 A A 844 A U 845 A A
867 A G 868 A G 869 A U 883 A C 884 A G 887 A U
888 A C 889 A C 890 A U 1359 A C 1462 A A 1463 A
U 1464 A A 1465 A C 1466 A C 1467 A U 1473 A C
1474 A G 1475 A G 1837 A C 2056 A U 2057 A G 2058
A U 2059 A C 2071 A G 2072 A G 2073 A A 2074 A G
2075 A U 2076 A A 2096 A C 2098 A G 2099 A A 2100
A U 2478 A A 2488 A G 2489 A C 2534 A U 2539 A NA
8305 A NA 8363 A

1.37

171.2

-0.40

-0.73

4.2

A 629 A A 630 A A 631 A C 633 A G 634 A A 635 A A
788 A C 789 A U 825 A A 827 A G 828 A A 829 A G
830 A U 831 A C 839 A U 845 A A 846 A C 847 A C
848 A C 849 A U 850 A U 1359 A A 1406 A A 1407 A
U 1408 A C 1534 A G 1535 A C 1536 A C 1537 A U
1539 A A 1642 A C 1643 A U 1645 A G 1646 A G 1647
A A 1682 A G 1695 A U 1696 A G 1697 A U 1698 A C
1699 A C 1700 A A 1701 A G 1837 A U 1838 A C 2056
A U 2057 A G 2058 A U 2059 A C 2071 A G 2072 A G
2073 A A 2074 A G 2075 A U 2076 A A 2096 A C 2098
A G 2099 A A 2100 A A 2488 A G 2489 A C 2534 A U
2539 A C 2644 A U 2645 A G 2646 A NA 8305 A NA
8363 A NA 8379 A

1.32

181.2

-0.49

-0.80

3.4

110

A 629 A A 630 A A 631 A A 913 A A 914 A C 915 A A
929 A C 930 A G 940 A G 941 A U 942 A A 943 A U
1017 A A 1018 A C 1019 A A 1020 A G 1021 A A 1022
A C 1023 A G 1046 A U 1047 A G 1048 A C 1049 A C
1051 A A 1058 A G 1059 A C 1060 A C 1061 A U 1062
A G 1063 A U 1064 A G 1065 A U 1066 A C 1126 A C
1127 A U 1128 A C 1129 A U 1130 A A 1233 A U 1234
A U 2059 A A 2060 A C 2061 A A 2062 A C 2065 A C
2066 A G 2068 A U 2069 A C 2071 A G 2072 A G 2073
A A 2074 A G 2075 A U 2076 A G 2094 A A 2095 A A
2096 A C 2393 A A 2488 A G 2489 A A 2490 A G 2491
A U 2492 A C 2493 A G 2524 A G 2525 A C 2534 A U
2539 A NA 8305 A C 3091 B G 3092 B A 3093 B

1.20

1.35

192.8

-0.45

-0.73

5.1

C 764 A G 765 A A 766 A A 767 A U 768 A G 787 A A
788 A C 789 A U 825 A A 827 A G 828 A A 829 A G
830 A U 831 A C 839 A U 845 A A 846 A C 847 A C
848 A C 849 A U 850 A U 883 A C 884 A U 888 A A
895 A C 896 A A 897 A U 1359 A C 1360 A C 1361 A
A 1406 A A 1407 A U 1408 A G 1490 A G 1491 A A
1493 A A 1528 A G 1529 A U 1530 A U 1531 A G 1532
A G 1535 A C 1536 A C 1537 A C 1613 A G 1614 A A
1615 A A 1616 A C 1617 A A 1642 A C 1643 A C 1644
A A 1661 A C 1662 A G 1663 A A 1682 A G 1695 A U
1696 A G 1697 A U 1698 A C 1699 A C 1700 A A 1701
A G 1837 A U 1838 A G 2099 A A 2100 A A 2101 A C
2477 A U 2478 A A 2479 A G 2480 A C 2644 A U 2645
A G 2646 A NA 8379 A

1.27

1.95

198.1

-0.42

-0.72

5.0

C 764 A G 765 A A 766 A A 767 A U 768 A A 788 A C
789 A U 825 A A 827 A G 828 A A 829 A G 830 A U
831 A C 839 A U 845 A A 846 A C 847 A C 848 A C
849 A U 850 A U 883 A C 884 A U 888 A A 895 A C
896 A A 897 A U 1359 A C 1360 A C 1361 A A 1406 A
A 1407 A U 1408 A U 1488 A G 1496 A U 1505 A U
1544 A C 1545 A G 1571 A A 1572 A C 1617 A G 1618
A G 1619 A C 1620 A G 1636 A A 1637 A A 1641 A A
1642 A C 1643 A A 1682 A G 1695 A U 1696 A G 1697
A U 1698 A C 1699 A C 1700 A A 1701 A G 1837 A U
1838 A G 2099 A A 2100 A A 2101 A C 2477 A U 2478
A A 2479 A G 2480 A C 2644 A U 2645 A G 2646 A NA
8379 A

1.20

201.5

-0.48

-0.71

5.3

U 468 A U 825 A G 828 A G 830 A U 831 A C 839 A C
842 A A 843 A A 844 A U 845 A A 846 A C 847 A C
848 A C 849 A U 850 A C 851 A A 882 A G 1378 A A
1379 A A 1407 A G 1688 A A 1689 A C 1692 A A 1693
A G 1694 A A 1712 A G 1713 A C 1753 A G 1756 A U
1757 A U 1758 A A 1759 A U 1817 A C 1818 A G 1820
A A 1821 A A 1822 A G 1823 A C 1824 A U 1825 A C
1826 A G 1827 A G 1828 A A 1829 A G 1837 A U 1838
A G 1884 A A 1885 A A 1886 A U 1887 A C 1888 A C
1889 A A 2011 A G 2013 A G 2014 A A 2015 A U 2016
A U 2017 A A 2018 A A 2019 A C 2020 A C 2021 A A
2022 A G 2023 A G 2099 A A 2100 A C 2644 A U 2645
A G 2646 A MG 8083 A NA 8379 A

1.22

203.0

-0.64

-0.71

7.2

U 468 A A 788 A C 789 A U 825 A A 827 A G 828 A A
829 A G 830 A U 831 A C 839 A C 842 A A 843 A A
844 A U 845 A A 846 A C 847 A C 848 A C 849 A U
850 A A 882 A A 1406 A A 1407 A U 1408 A G 1410 A
U 1488 A G 1496 A G 1497 A U 1505 A C 1545 A G
1546 A A 1547 A U 1548 A C 1549 A A 1550 A C 1551
A G 1563 A C 1564 A C 1565 A C 1566 A A 1567 A G
1568 A U 1569 A C 1617 A A 1641 A A 1642 A C 1643
A A 1682 A G 1688 A A 1689 A C 1692 A A 1693 A G
1694 A G 1695 A U 1696 A G 1697 A U 1698 A C 1699
A C 1700 A A 1701 A A 1717 A G 1837 A U 1838 A G
2099 A A 2100 A C 2644 A U 2645 A G 2646 A A 2880
A C 2881 A NA 8379 A

1.20

1.36

202.0

-0.48

-0.72

5.5

C 764 A G 765 A A 766 A A 767 A U 768 A U 825 A G
828 A G 830 A U 831 A C 839 A U 845 A A 846 A C
847 A C 848 A C 849 A U 850 A U 883 A C 884 A U
888 A A 895 A C 896 A A 897 A U 1359 A C 1360 A C
1361 A G 1378 A A 1379 A A 1407 A A 1712 A G 1713
A G 1739 A U 1740 A G 1756 A C 1808 A G 1809 A C
1816 A U 1817 A G 1837 A U 1838 A G 2099 A A 2100
A A 2101 A C 2477 A U 2478 A A 2479 A G 2480 A C
2644 A U 2645 A G 2646 A G 2730 A G 2731 A U 2732
A A 2741 A G 2742 A A 2743 A G 2744 A U 2749 A G
2750 A C 2751 A C 2752 A U 2866 A G 2867 A C 2868
A A 2885 A C 2886 A NA 8379 A

1.20

217.6

-1.19

-0.80

13.4

C 31 A G 33 A C 34 A U 35 A G 50 A C 62 A U 63 A
C 85 A A 86 A A 151 A A 174 A U 176 A A 177 A C
208 A G 213 A U 214 A G 223 A U 224 A G 225 A C
440 A A 441 A A 442 A C 443 A A 459 A C 461 A A
462 A A 463 A G 464 A A 466 A G 467 A U 468 A A
476 A G 479 A C 480 A G 514 A U 647 A G 648 A U
649 A C 650 A U 651 A G 661 A G 681 A A 682 A G
683 A G 684 A C 685 A A 686 A C 687 A G 689 A G
690 A G 691 A C 757 A A 758 A C 759 A C 842 A A
843 A A 844 A A 882 A A 1427 A C 1428 A G 1688 A
A 1689 A C 1692 A A 1693 A G 1694 A NA 8341 A

1.33

21.4

-0.40

-0.80

3.4

A 1173 A C 1176 A A 1177 A G 1178 A C 1179 A A
1181 A A 1194 A G 1195 A G 1197 A U 1198 A C 1201
A A 1202 A

1.32

1.54

18.7

-1.32

-0.64

17.6

C 136 A U 137 A C 139 A A 261 A

1.31

1.52

25.6

-1.28

-0.70

17.4

C 136 A U 137 A G 259 A C 260 A A 261 A

1.14

17.9

-0.53

-0.81

5.0

A 485 A A 486 A G 487 A U 488 A G 504 A C 505 A G
512 A

1.30

1.39

20.7

-1.30

-0.51

18.1

G 964 A A 965 A U 966 A

Residue-type_colouring

Positive	Negative	Neutral	Aliphatic	Aromatic	Pro & Gly	Cysteine
H,K,R	D,E	S,T,N,Q	A,V,L,I,M	F,Y,W	P,G	C

Acknowledgement

Tunnels were calculated by

MOLE 2.0 program version 2.5.13.11.08 and visualized using Pymol 0.97rc.