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UniProt functional annotation for P21963 | ||
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| UniProt code: P21963. |
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| Organism: | |
Crotalus atrox (Western diamondback rattlesnake). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus. |
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| Function: | |
Galactose-binding protein which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids. Calcium- dependent lectin. Shows high hemagglutinating activity (MHC=10 ng/ml) (PubMed:1989986). {ECO:0000269|PubMed:1989986}. |
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| Subunit: | |
Homodecamer of disulfide-linked dimers arranged in two pseudo- 5-fold symmetric pentamers. {ECO:0000269|PubMed:15049685}. |
| Subcellular location: | |
Secreted {ECO:0000269|PubMed:1989986}. |
| Tissue specificity: | |
Expressed by the venom gland. {ECO:0000305|PubMed:1989986}. |
| Mass spectrometry: | |
Mass=16284; Method=Unknown; Note=Average mass.; Evidence={ECO:0000269|PubMed:19371136}; |
| Similarity: | |
Belongs to the true venom lectin family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.