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UniProt functional annotation for Q7LZK8 | ||
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| UniProt code: Q7LZK8. |
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| Organism: | |
Bitis arietans (African puff adder). |
| Taxonomy: | |
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Viperinae; Bitis. |
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| Function: | |
Snaclec that binds to von Willebrand factor (VWF) and induces its interaction with GPIbalpha (GP1BA) (via the vWF A1 domain), resulting in platelet aggregation. {ECO:0000269|PubMed:12069583, ECO:0000269|PubMed:8806626}. |
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| Subunit: | |
Heterodimer of subunits alpha and beta; disulfide-linked. {ECO:0000269|PubMed:11695907, ECO:0000269|PubMed:12851390}. |
| Subcellular location: | |
Secreted. |
| Tissue specificity: | |
Expressed by the venom gland. |
| Similarity: | |
Belongs to the snaclec family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.