UniProt functional annotation for Q09734

UniProt code: Q09734.

Organism: Trypanosoma cruzi.
Taxonomy: Eukaryota; Euglenozoa; Kinetoplastida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
 
Function: Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.
 
Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).
Enzyme regulation: Strongly inhibited by FK506 and L-685,818.
Subcellular location: Secreted, extracellular space.
Similarity: Belongs to the FKBP-type PPIase family.
Similarity: Contains 1 PPIase FKBP-type domain.

Annotations taken from UniProtKB at the EBI.