PDBsum entry 1jim

Hydrolase(serine proteinase)

PDB id: 1jim

Contents

Protein chain

240 a.a. *

Ligands

SO4

ICU

Waters ×133

* Residue conservation analysis

PDB id:

1jim

Name:

Hydrolase(serine proteinase)

Title:

Stereospecific reaction of 3-methoxy-4-chloro-7-aminoisocoumarin with crystalline porcine pancreatic elastase

Structure:

Porcine pancreatic elastase. Chain: a. Engineered: yes

Source:

Sus scrofa domestica. Domestic pig. Organism_taxid: 9825. Strain: domestica

Resolution:

2.31Å R-factor: 0.153

Authors:

E.Meyer

Key ref:

E.F.Meyer junior et al. (1985). Stereospecific reaction of 3-Methoxy-4-Chloro-7-Aminoisocoumarin with crystalline porcine pancreatic elastase. J am chem soc, 107, 4091.

Date:

19-Mar-93 Release date: 31-Jan-94

Protein chain

P00772  (CELA1_PIG) -  Chymotrypsin-like elastase family member 1 from Sus scrofa

Seq: 266 a.a.

Struc: 240 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.21.36 - pancreatic elastase.
• Reaction: Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.