PDBsum entry 1jg8

Lyase

PDB id: 1jg8

Contents

Protein chains

343 a.a. *

Metals

_NA ×2

_CA ×6

Waters ×841

* Residue conservation analysis

PDB id:

1jg8

Name:

Lyase

Title:

Crystal structure of threonine aldolase (low-specificity)

Structure:

L-allo-threonine aldolase. Chain: a, b, c, d. Engineered: yes

Source:

Thermotoga maritima. Organism_taxid: 2336. Gene: tm1744. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Biol. unit:

Tetramer (from PQS)

Resolution:

1.80Å R-factor: 0.207 R-free: 0.222

Authors:

C.L.Kielkopf,J.Bonanno,S.Ray,S.K.Burley,New York Sgx Research Center For Structural Genomics (Nysgxrc)

Key ref:

C.L.Kielkopf et al. Crystal structure of low-Specificity threonine aldolase, A key enzyme in glycine biosynthesis. To be published, .

Date:

23-Jun-01 Release date: 04-Jul-01

Protein chains

Q9X266  (Q9X266_THEMA) -  L-allo-threonine aldolase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)

Seq: 343 a.a.

Struc: 343 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.4.1.2.5 - L-threonine aldolase.
• Reaction: L-threonine = acetaldehyde + glycine
• Cofactor: Pyridoxal 5'-phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site