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UniProt functional annotation for Q8U4J3 | ||
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| UniProt code: Q8U4J3. |
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| Organism: | |
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1). |
| Taxonomy: | |
Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus. |
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| Function: | |
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. {ECO:0000269|PubMed:11274122, ECO:0000269|PubMed:12296822}. |
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| Subunit: | |
Heteromultimer composed of three to four small subunits (RfcS) and one to two large subunits (RfcL). {ECO:0000269|PubMed:11274122}. |
| Ptm: | |
This protein undergoes a protein self splicing that involves a post-translational excision of the intervening region (intein) followed by peptide ligation. {ECO:0000305}. |
| Miscellaneous: | |
The intein interrupts the potential ATP-binding site. |
| Similarity: | |
Belongs to the activator 1 small subunits family. RfcS subfamily. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.