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PDBsum entry 1inc
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Hydrolase(serine proteinase)
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PDB id
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1inc
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References listed in PDB file
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Key reference
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Title
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Crystal structures of the complex of porcine pancreatic elastase with two valine-Derived benzoxazinone inhibitors.
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Authors
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R.Radhakrishnan,
L.G.Presta,
E.F.Meyer,
R.Wildonger.
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Ref.
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J Mol Biol, 1987,
198,
417-424.
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PubMed id
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Abstract
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The crystal structures of porcine pancreatic elastase complexed to two similar
benzoxazinone inhibitors are reported to 2.09 A and 1.76 A resolution, and
refined to conventional R factors of 0.153 and 0.172.
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Secondary reference #1
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Title
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Design, Synthesis, And kinetic evaluation of a unique class of elastase inhibitors, The peptidyl alpha-Ketobenzoxazoles, And the x-Ray crystal structure of the covalent complex between porcine pancreatic elastase and ac-Ala-Pro-Val-2-Benzoxazole
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Authors
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P.D.Edwards,
E.F.Meyer junior,
J.Vijayalakshmi,
P.A.Tuthill,
D.A.Andisik,
B.Gomes,
A.Strimpler.
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Ref.
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j am chem soc, 1992,
114,
1854.
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