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UniProt functional annotation for P82409 | ||
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| UniProt code: P82409. |
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| Organism: | |
Momordica cochinchinensis (Spiny bitter cucumber) (Muricia cochinchinensis). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Cucurbitales; Cucurbitaceae; Momordiceae; Momordica. |
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| Function: | |
Inhibits trypsin; probably participates in a plant defense mechanism. |
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| Subcellular location: | |
Secreted. |
| Domain: | |
The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin. {ECO:0000250}. |
| Ptm: | |
A cyclic succinimide probably forms by loss of water between Asp-4 and Gly-5, that can then rehydrate to either the original peptide bond or to a beta-aspartyl isopeptide bond. Three isoforms of MCoTI-II are detected, two with the parent molecular weight, corresponding to the unmodified and proposed isopeptide forms, and one with a molecular weight 18 Da lower, corresponding to a succinimide cross-linked form. |
| Ptm: | |
This is a cyclic peptide. |
| Mass spectrometry: | |
Mass=3453; Mass_error=0.2; Method=Electrospray; Evidence={ECO:0000269|PubMed:10801322}; |
| Similarity: | |
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.