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UniProt functional annotation for P29600 | ||
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| UniProt code: P29600. |
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| Organism: | |
Lederbergia lentus (Bacillus lentus). |
| Taxonomy: | |
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Lederbergia. |
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| Function: | |
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. |
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| Catalytic activity: | |
Reaction=Hydrolysis of proteins with broad specificity for peptide bonds, and a preference for a large uncharged residue in P1. Hydrolyzes peptide amides.; EC=3.4.21.62; |
| Cofactor: | |
Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Note=Binds 2 calcium ions per subunit.; |
| Subcellular location: | |
Secreted. |
| Biotechnology: | |
Used as a detergent protease. Sold under the name Savinase by Novozymes. |
| Miscellaneous: | |
Secretion of subtilisin is associated with onset of sporulation, and many mutations which block sporulation at early stages affect expression levels of subtilisin. However, subtilisin is not necessary for normal sporulation. |
| Similarity: | |
Belongs to the peptidase S8 family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.