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UniProt functional annotation for O48917 | ||
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| UniProt code: O48917. |
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| Organism: | |
Arabidopsis thaliana (Mouse-ear cress). |
| Taxonomy: | |
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. |
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| Function: | |
Involved in the biosynthesis of sulfolipids found in thylakoid membranes. Converts UDP-glucose and sulfite to the sulfolipid head group precursor UDP-sulfoquinovose. {ECO:0000269|PubMed:11073956}. |
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| Catalytic activity: | |
Reaction=H(+) + sulfite + UDP-alpha-D-glucose = H2O + UDP-alpha-D-6- sulfoquinovose; Xref=Rhea:RHEA:13197, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17359, ChEBI:CHEBI:58885, ChEBI:CHEBI:60009; EC=3.13.1.1; |
| Cofactor: | |
Name=NAD(+); Xref=ChEBI:CHEBI:57540; |
| Activity regulation: | |
Concentrations above 100 uM sulfite inhibit the reaction. |
| Biophysicochemical properties: | |
Kinetic parameters: KM=150 uM for UDP-glucose; KM=10 uM for sulfite; pH dependence: Optimum pH is 7.5-9.5.; |
| Subunit: | |
Homodimer. {ECO:0000269|PubMed:10557279}. |
| Subcellular location: | |
Plastid, chloroplast {ECO:0000269|PubMed:9465123}. |
| Induction: | |
Induced in response to altered availability of inorganic phosphate. {ECO:0000269|PubMed:12805589, ECO:0000269|PubMed:9465123}. |
| Similarity: | |
Belongs to the NAD(P)-dependent epimerase/dehydratase family. {ECO:0000305}. |
Annotations taken from UniProtKB at the EBI.