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PDBsum entry 1grl
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References listed in PDB file
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Key reference
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Title
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The crystal structure of the bacterial chaperonin groel at 2.8 a.
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Authors
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K.Braig,
Z.Otwinowski,
R.Hegde,
D.C.Boisvert,
A.Joachimiak,
A.L.Horwich,
P.B.Sigler.
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Ref.
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Nature, 1994,
371,
578-586.
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PubMed id
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Abstract
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The crystal structure of Escherichia coli GroEL shows a porous cylinder of 14
subunits made of two nearly 7-fold rotationally symmetrical rings stacked
back-to-back with dyad symmetry. The subunits consist of three domains: a large
equatorial domain that forms the foundation of the assembly at its waist and
holds the rings together; a large loosely structured apical domain that forms
the ends of the cylinder; and a small slender intermediate domain that connects
the two, creating side windows. The three-dimensional structure places most of
the mutationally defined functional sites on the channel walls and its outward
invaginations, and at the ends of the cylinder.
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Secondary reference #1
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Title
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Residues in chaperonin groel required for polypeptide binding and release.
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Authors
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W.A.Fenton,
Y.Kashi,
K.Furtak,
A.L.Horwich.
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Ref.
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Nature, 1994,
371,
614-619.
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PubMed id
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